Spyre Therapeutics, Inc. (SYRE)

Spyre Therapeutics is a clinical-stage biotechnology firm developing next-generation antibody therapies for inflammatory bowel disease and other immune-mediated conditions. Its pipeline centers on extended half-life monoclonal antibodies against validated targets such as α4β7, TL1A and IL-23, including combination regimens aimed at deeper and more durable disease control. The company focuses on patients with ulcerative colitis, Crohn’s disease and related rheumatic indications, seeking simpler dosing and more complete response than existing biologics.

Market
Nasdaq
Sector
Healthcare
Trend
Neutral
Last close
88.98 (+1.98% on the day)
MA50
98.08
MA200
61.99
52-week range
14.82–108.92
Market cap
7.9B USD
Dividend yield
0%
Data as of
2026-09-04
Quarterly revenue and earnings, millions of USD
QuarterRevenueYoY %EarningsYoY %
Q1 20250-44.8
Q2 20250-36.7
Q3 20250-11.2
Q4 20250-62.5
Q1 20260-69
Q2 20260-36.2

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