Sionna Therapeutics, Inc. (SION)

Sionna Therapeutics is a clinical-stage biopharmaceutical company focused exclusively on cystic fibrosis. It develops small-molecule medicines designed to stabilize CFTR’s nucleotide-binding domain 1 (NBD1), aiming to correct defects linked to the common F508del mutation and more fully restore CFTR function. Its pipeline of NBD1 stabilizers and complementary CFTR modulators targets people with CF who may still have unmet need despite existing modulator therapies.

Market
Nasdaq
Trend
Strong downtrend
Last close
3.87 (-6.75% on the day)
MA50
5.77
MA200
31.32
52-week range
3.87–51.04
Market cap
221.5M USD
Dividend yield
0%
Data as of
2026-06-30
Quarterly revenue and earnings, millions of USD
QuarterRevenueYoY %EarningsYoY %
Q2 20250—-18.1—
Q3 20250—-20.3—
Q4 20250—-20.4—
Q1 20260—-26.8—
Q2 20260—-29.9—

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